Domestic Box Office Results for 2021 Week 11 (3-Day Mar 12 - Mar 14)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | -29.7% | 1,474 | -99 | $288,671 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -7.5% | 2,546 | -25 | $158,814 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 12.5% | 3,506 | 42 | $97,297 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -19.6% | 1,862 | -65 | $175,273 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 15.0% | 3,548 | 50 | $57,059 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | -28.7% | 1,323 | -96 | $125,437 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -3.0% | 2,569 | -10 | $49,215 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 15.3% | 3,443 | 51 | $35,416 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | 18.6% | 3,570 | 62 | $30,483 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | 25.1% | 3,854 | 84 | $26,808 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | -8.8% | 2,121 | -29 | $45,281 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | -21.6% | 1,442 | -72 | $58,253 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | -18.1% | 1,573 | -60 | $51,102 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | 1.3% | 2,504 | 4 | $30,122 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | 16.2% | 3,212 | 54 | $22,890 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | -5.2% | 2,101 | -17 | $33,826 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | 27.9% | 3,717 | 93 | $17,514 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -12.0% | 1,680 | -40 | $38,533 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | -22.0% | 1,138 | -73 | $43,196 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 8.8% | 2,641 | 29 | $18,387 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | 29.5% | 3,634 | 98 | $13,226 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | 13.8% | 2,810 | 46 | $13,945 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -7.0% | 1,731 | -23 | $21,137 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -10.4% | 1,521 | -35 | $22,985 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | 28.6% | 3,428 | 95 | $8,377 | $28,717,189 | 1 |