Domestic Box Office Results for 2021 Week 24 (3-Day Jun 11 - Jun 13)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | 17.6% | 3,840 | 59 | $110,808 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -29.3% | 1,453 | -98 | $278,279 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 25.2% | 4,140 | 84 | $82,397 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -20.6% | 1,811 | -69 | $180,209 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 14.0% | 3,499 | 47 | $57,858 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 16.2% | 3,568 | 54 | $46,512 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -17.8% | 1,830 | -59 | $69,089 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 20.2% | 3,691 | 67 | $33,036 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | 0.2% | 2,649 | 1 | $41,081 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -1.9% | 2,503 | -6 | $41,277 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 7.0% | 2,910 | 23 | $33,003 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | 22.4% | 3,641 | 75 | $23,071 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | 12.4% | 3,098 | 41 | $25,947 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | 26.8% | 3,782 | 89 | $19,943 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | -17.0% | 1,548 | -57 | $47,496 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | -28.7% | 926 | -96 | $76,747 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | 19.9% | 3,313 | 66 | $19,649 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | 28.1% | 3,684 | 94 | $17,572 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | 13.2% | 2,902 | 44 | $16,939 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | -21.0% | 1,149 | -70 | $42,262 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | 11.6% | 2,739 | 39 | $17,547 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | -13.9% | 1,426 | -46 | $27,479 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | 7.3% | 2,443 | 24 | $14,977 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | 11.6% | 2,618 | 39 | $13,354 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | 24.9% | 3,247 | 83 | $8,844 | $28,717,189 | 1 |