Domestic Box Office Results for 2021 Week 3 (3-Day Jan 15 - Jan 17)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | 4.6% | 3,190 | 15 | $133,386 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | 28.5% | 4,346 | 95 | $93,037 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | -17.4% | 2,012 | -58 | $169,544 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -29.2% | 1,380 | -97 | $236,492 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | -16.1% | 1,997 | -54 | $101,374 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 10.2% | 3,271 | 34 | $50,735 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | 0.6% | 2,748 | 2 | $46,009 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | -5.9% | 2,383 | -20 | $51,169 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | -22.2% | 1,531 | -74 | $71,080 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -0.4% | 2,578 | -1 | $40,076 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 24.9% | 3,805 | 83 | $25,240 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | 25.6% | 3,801 | 85 | $22,100 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | 16.6% | 3,309 | 55 | $24,292 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -12.2% | 1,832 | -41 | $41,172 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | -27.9% | 1,006 | -93 | $73,086 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | -5.3% | 2,093 | -18 | $33,955 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | -23.9% | 1,123 | -80 | $57,968 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -19.0% | 1,329 | -63 | $48,709 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | -1.5% | 2,166 | -5 | $22,695 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | -5.9% | 1,906 | -20 | $25,477 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -5.4% | 1,890 | -18 | $25,430 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | 16.1% | 2,923 | 54 | $13,406 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | 17.3% | 2,946 | 58 | $12,420 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -2.0% | 1,938 | -7 | $18,039 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | -29.2% | 540 | -97 | $53,180 | $28,717,189 | 1 |