Domestic Box Office Results for 2021 Week 47 (3-Day Nov 19 - Nov 21)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | 12.9% | 3,603 | 43 | $118,096 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -12.4% | 2,301 | -41 | $175,724 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 10.3% | 3,395 | 34 | $100,478 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | 20.7% | 3,876 | 69 | $84,200 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 28.2% | 4,208 | 94 | $48,109 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 7.8% | 3,152 | 26 | $52,650 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | 12.5% | 3,345 | 42 | $37,797 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 4.4% | 2,898 | 15 | $42,076 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | -29.8% | 1,148 | -99 | $94,794 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | 10.3% | 3,117 | 34 | $33,146 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 4.7% | 2,794 | 16 | $34,374 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | -4.1% | 2,313 | -14 | $36,317 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | -23.7% | 1,294 | -79 | $62,120 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -4.5% | 2,213 | -15 | $34,083 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | 23.8% | 3,588 | 79 | $20,492 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | -17.0% | 1,510 | -57 | $47,065 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | -3.9% | 2,123 | -13 | $30,663 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -19.8% | 1,292 | -66 | $50,104 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | 6.0% | 2,542 | 20 | $19,338 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 0.7% | 2,237 | 2 | $21,707 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | 10.3% | 2,674 | 34 | $17,974 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | 24.3% | 3,336 | 81 | $11,746 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -2.0% | 1,982 | -7 | $18,460 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -11.9% | 1,445 | -40 | $24,194 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | 3.7% | 2,187 | 12 | $13,131 | $28,717,189 | 1 |