Domestic Box Office Results for 2021 Week 5 (3-Day Jan 29 - Jan 31)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | -10.0% | 2,462 | -33 | $172,827 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -6.4% | 2,601 | -21 | $155,456 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | -5.6% | 2,600 | -19 | $131,201 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -26.2% | 1,531 | -87 | $213,167 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 28.5% | 4,227 | 95 | $47,893 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | -18.2% | 1,852 | -61 | $89,607 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -11.4% | 2,148 | -38 | $58,861 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 27.4% | 4,050 | 91 | $30,108 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | 15.7% | 3,424 | 52 | $31,783 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -1.1% | 2,543 | -4 | $40,628 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | -7.8% | 2,171 | -26 | $44,238 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | -9.6% | 2,040 | -32 | $41,177 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | -4.1% | 2,274 | -14 | $35,349 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -5.7% | 2,155 | -19 | $35,001 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | 2.0% | 2,498 | 7 | $29,433 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | -22.4% | 1,239 | -75 | $57,359 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | 21.2% | 3,381 | 71 | $19,254 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -24.0% | 1,080 | -80 | $59,940 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | -15.1% | 1,487 | -50 | $33,058 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | -9.0% | 1,750 | -30 | $27,748 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | 9.4% | 2,632 | 31 | $18,261 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | 10.0% | 2,618 | 33 | $14,968 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -14.6% | 1,351 | -49 | $27,082 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -16.0% | 1,238 | -53 | $28,239 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | -26.4% | 681 | -88 | $42,169 | $28,717,189 | 1 |