Domestic Box Office Results for 2022 Week 38 (3-Day Sep 16 - Sep 18)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | 28.5% | 4,385 | 95 | $97,036 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -1.0% | 2,872 | -3 | $140,787 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 11.7% | 3,463 | 39 | $98,505 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | 18.4% | 3,761 | 61 | $86,775 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 5.3% | 3,066 | 18 | $66,029 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 27.1% | 4,113 | 90 | $40,348 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -7.3% | 2,353 | -24 | $53,732 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 15.3% | 3,446 | 51 | $35,385 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | 12.7% | 3,273 | 42 | $33,249 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | 15.5% | 3,374 | 52 | $30,621 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 26.3% | 3,877 | 88 | $24,772 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | 4.2% | 2,728 | 14 | $30,792 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | -10.0% | 1,981 | -33 | $40,577 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -16.9% | 1,593 | -56 | $47,349 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | -21.0% | 1,351 | -70 | $54,422 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | 14.3% | 3,076 | 48 | $23,104 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | 24.7% | 3,554 | 82 | $18,317 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -26.7% | 947 | -89 | $68,358 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | -3.7% | 2,056 | -12 | $23,909 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 0.1% | 2,204 | - | $22,032 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -22.9% | 1,014 | -76 | $47,398 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | -24.9% | 877 | -83 | $44,681 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | 22.7% | 3,215 | 76 | $11,381 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | 25.7% | 3,326 | 86 | $10,511 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | -23.7% | 813 | -79 | $35,322 | $28,717,189 | 1 |