Domestic Box Office Results for 2022 Week 39 (3-Day Sep 23 - Sep 25)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | 25.3% | 4,224 | 84 | $100,734 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -28.0% | 1,522 | -93 | $265,664 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 13.5% | 3,554 | 45 | $95,983 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -21.3% | 1,773 | -71 | $184,072 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | -19.1% | 1,844 | -64 | $109,785 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | -11.2% | 2,200 | -37 | $75,433 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -4.7% | 2,484 | -16 | $50,899 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | -10.4% | 2,159 | -35 | $56,478 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | -18.2% | 1,731 | -61 | $62,868 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -2.9% | 2,457 | -10 | $42,050 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 0.7% | 2,593 | 2 | $37,038 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | 16.2% | 3,332 | 54 | $25,210 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | -6.1% | 2,176 | -20 | $36,941 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -25.1% | 1,185 | -84 | $63,651 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | 13.1% | 3,057 | 44 | $24,051 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | 3.5% | 2,534 | 12 | $28,046 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | -22.9% | 1,175 | -76 | $55,403 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | 9.7% | 2,767 | 32 | $23,395 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | 27.4% | 3,610 | 91 | $13,617 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | -27.0% | 852 | -90 | $56,995 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -19.7% | 1,173 | -66 | $40,974 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | 7.6% | 2,499 | 25 | $15,680 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | 22.0% | 3,181 | 73 | $11,502 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -26.2% | 730 | -87 | $47,890 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | -18.8% | 1,060 | -63 | $27,092 | $28,717,189 | 1 |