Domestic Box Office Results for 2022 Week 40 (3-Day Sep 30 - Oct 2)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | -21.8% | 1,872 | -73 | $227,297 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | 11.1% | 3,477 | 37 | $116,290 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 3.4% | 3,051 | 11 | $111,807 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | 26.6% | 4,171 | 89 | $78,245 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | -11.4% | 2,232 | -38 | $90,701 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 26.1% | 4,066 | 87 | $40,815 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -4.1% | 2,516 | -14 | $50,251 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 24.5% | 3,906 | 82 | $31,218 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | 20.7% | 3,677 | 69 | $29,596 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | 4.3% | 2,815 | 14 | $36,702 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 6.0% | 2,862 | 20 | $33,557 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | -18.9% | 1,575 | -63 | $53,334 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | 5.7% | 2,765 | 19 | $29,072 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -15.3% | 1,674 | -51 | $45,058 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | -1.1% | 2,343 | -4 | $31,380 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | - | 2,361 | - | $30,101 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | 8.8% | 2,762 | 29 | $23,569 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | 4.7% | 2,517 | 16 | $25,719 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | -1.0% | 2,190 | -3 | $22,446 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 22.5% | 3,327 | 75 | $14,596 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -9.8% | 1,671 | -33 | $28,762 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | 28.8% | 3,558 | 96 | $11,013 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -24.6% | 851 | -82 | $42,995 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | 1.4% | 2,109 | 5 | $16,577 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | -2.8% | 1,860 | -9 | $15,439 | $28,717,189 | 1 |