Domestic Box Office Results for 2022 Week 42 (3-Day Oct 14 - Oct 16)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | 23.5% | 4,135 | 78 | $102,902 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -10.8% | 2,380 | -36 | $169,891 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 9.3% | 3,346 | 31 | $101,949 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -7.3% | 2,475 | -24 | $131,862 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 10.8% | 3,340 | 36 | $60,612 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | -7.9% | 2,367 | -26 | $70,111 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -3.2% | 2,558 | -11 | $49,426 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | -26.2% | 1,368 | -87 | $89,134 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | -10.8% | 2,102 | -36 | $51,772 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -6.6% | 2,268 | -22 | $45,554 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | -0.3% | 2,543 | -1 | $37,766 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | 9.8% | 3,009 | 33 | $27,917 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | 5.6% | 2,762 | 19 | $29,103 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | -27.5% | 1,065 | -92 | $70,823 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | 16.0% | 3,198 | 53 | $22,991 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | -3.7% | 2,174 | -12 | $32,690 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | 19.8% | 3,310 | 66 | $19,667 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -24.1% | 1,077 | -80 | $60,107 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | -8.3% | 1,824 | -28 | $26,950 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 22.1% | 3,303 | 74 | $14,702 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -14.6% | 1,432 | -49 | $33,563 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | -23.5% | 944 | -78 | $41,510 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -24.6% | 849 | -82 | $43,096 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | 26.4% | 3,360 | 88 | $10,405 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | 7.5% | 2,374 | 25 | $12,097 | $28,717,189 | 1 |