Domestic Box Office Results for 2022 Week 43 (3-Day Oct 21 - Oct 23)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | -26.6% | 1,631 | -89 | $260,883 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | 19.0% | 3,868 | 63 | $104,535 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | -29.2% | 1,420 | -97 | $240,227 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | 23.8% | 4,032 | 79 | $80,942 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | 12.3% | 3,415 | 41 | $59,281 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 23.1% | 3,917 | 77 | $42,367 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | -10.9% | 2,175 | -36 | $58,130 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 16.4% | 3,499 | 55 | $34,849 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | 1.7% | 2,724 | 6 | $39,950 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -15.2% | 1,840 | -51 | $56,150 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 8.2% | 2,969 | 27 | $32,348 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | 21.1% | 3,573 | 70 | $23,510 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | -26.5% | 1,155 | -88 | $69,595 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | 12.6% | 3,071 | 42 | $24,561 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | -27.8% | 1,012 | -93 | $72,652 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | 21.7% | 3,447 | 72 | $20,617 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | -16.1% | 1,516 | -54 | $42,941 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | -0.8% | 2,242 | -3 | $28,874 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | 18.0% | 3,139 | 60 | $15,660 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 25.7% | 3,485 | 86 | $13,934 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -1.7% | 2,077 | -6 | $23,140 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | -9.1% | 1,666 | -30 | $23,521 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -21.9% | 985 | -73 | $37,146 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -20.3% | 1,027 | -68 | $34,041 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | -10.7% | 1,467 | -36 | $19,575 | $28,717,189 | 1 |