Domestic Box Office Results for 2022 Week 45 (3-Day Nov 4 - Nov 6)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Super Mario Galaxy Movie | PG | Universal Pictures | $425,500,825 | -11.9% | 2,365 | -40 | $179,916 | $425,500,825 | 1 |
| 2 | Avatar: Fire and Ash | PG-13 | 20th Century Studios | $404,340,010 | -15.3% | 2,155 | -51 | $187,629 | $404,340,010 | 1 |
| 3 | Project Hail Mary | PG-13 | Amazon Studios | $341,121,909 | 9.8% | 3,370 | 33 | $101,223 | $341,121,909 | 1 |
| 4 | Michael | PG-13 | Lionsgate | $326,359,112 | -12.0% | 2,239 | -40 | $145,761 | $326,359,112 | 1 |
| 5 | The Devil Wears Prada 2 | PG-13 | Walt Disney Studios Motion Pictures | $202,443,724 | -11.0% | 2,248 | -37 | $90,055 | $202,443,724 | 1 |
| 6 | Hoppers | PG | Walt Disney Studios Motion Pictures | $165,953,089 | 22.4% | 3,878 | 75 | $42,793 | $165,953,089 | 1 |
| 7 | The Housemaid | R | Lionsgate | $126,432,462 | 1.1% | 2,776 | 4 | $45,545 | $126,432,462 | 1 |
| 8 | Scream 7 | NR | Paramount | $121,935,967 | 0.1% | 2,685 | - | $45,414 | $121,935,967 | 1 |
| 9 | Star Wars: The Mandalorian and Grogu | PG-13 | Walt Disney Studios Motion Pictures | $108,823,848 | -6.7% | 2,304 | -22 | $47,233 | $108,823,848 | 1 |
| 10 | GOAT | PG | Sony Pictures Releasing | $103,316,898 | -25.9% | 1,306 | -86 | $79,109 | $103,316,898 | 1 |
| 11 | Marty Supreme | R | A24 | $96,040,064 | 21.9% | 3,656 | 73 | $26,269 | $96,040,064 | 1 |
| 12 | Wuthering Heights | R | Warner Bros Pictures | $84,001,072 | -8.0% | 2,121 | -27 | $39,604 | $84,001,072 | 1 |
| 13 | David | PG | Angel Studios | $80,382,774 | 10.2% | 2,990 | 34 | $26,884 | $80,382,774 | 1 |
| 14 | Mortal Kombat II | R | Warner Bros Pictures | $75,426,256 | 26.1% | 3,744 | 87 | $20,146 | $75,426,256 | 1 |
| 15 | Obsession | R | Focus Features | $73,524,085 | 6.1% | 2,707 | 20 | $27,161 | $73,524,085 | 1 |
| 16 | The SpongeBob Movie: Search for SquarePants | PG | Paramount Pictures International | $71,068,170 | 19.5% | 3,335 | 65 | $21,310 | $71,068,170 | 1 |
| 17 | Anaconda | PG-13 | Sony Pictures Releasing | $65,098,148 | -21.6% | 1,240 | -72 | $52,499 | $65,098,148 | 1 |
| 18 | Send Help | R | Walt Disney Studios Motion Pictures | $64,734,795 | 8.9% | 2,725 | 30 | $23,756 | $64,734,795 | 1 |
| 19 | The Sheep Detectives | PG | Amazon Studios | $49,157,055 | 25.9% | 3,534 | 86 | $13,910 | $49,157,055 | 1 |
| 20 | Reminders of Him | PG-13 | Universal Pictures | $48,559,430 | 20.2% | 3,212 | 67 | $15,118 | $48,559,430 | 1 |
| 21 | The Drama | NR | A24 | $48,062,006 | -11.7% | 1,576 | -39 | $30,496 | $48,062,006 | 1 |
| 22 | Song Sung Blue | PG-13 | Focus Features | $39,185,290 | -13.9% | 1,423 | -46 | $27,537 | $39,185,290 | 1 |
| 23 | Crime 101 | R | Amazon Studios | $36,588,336 | -2.8% | 1,940 | -9 | $18,860 | $36,588,336 | 1 |
| 24 | Iron Lung | R | Independent | $34,960,000 | -7.2% | 1,680 | -24 | $20,810 | $34,960,000 | 1 |
| 25 | Lee Cronin's The Mummy | NR | Warner Bros Pictures | $28,717,189 | 11.6% | 2,579 | 39 | $11,135 | $28,717,189 | 1 |